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Despite being used locally (e.g.,injected near the injury site), BPC-157 seems to exert full-body effects

Intracellularly, GSH is maintained in its thiol-reduced form by NADPH-dependent enzymes (glutathione disulfide bond (GSSG) reductase)

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Here we show, by studying mice with B cell-specific ablation of the catalytic subunit of glutamate cysteine ligase ( Gclc ), that glutathione synthesis affects homeostasis and differentiation of MZB to a larger extent than FoB, while glutathione-dependent redox control contributes to the metabolic dependencies of FoB

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